ISDB News
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چکیده
The Congress will be held at Sydney’s famous Convention Centre, on the waterfront close to the Sydney Opera House. The organizers (Richard Harvey, Chair, Sally Dunwoodie, Peter Currie, Patrick Tam and others) have put together a very exciting program. There will be presentations by two Nobel laureates (Sydney Brenner and Christiane Nüsslein-Volhard), the winner of the 2005 ISDB Ross Harrison Prize (Elliot Meyerowitz, Caltech), ten plenary lecturers and over 60 scheduled Symposium speakers. An additional 40 oral Symposium presentations will be selected from submitted posters.
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ISDB News
In this time at which the Scientific Publishing world is changing so much, it is wonderful to note that Elsevier Ltd. contributes to the advancement of our scientific community through such a concrete step. Scientific Societies provide a way of advancing the interests of the community of scientists. Scientific journals depend on scientists to do the research, write papers, serve as editors and ...
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The human pathogen Staphylococcus aureus acquires heme iron from hemoglobin (Hb) via the action of a series of iron-regulated surface determinant (Isd) proteins. The cell wall anchored IsdB protein is recognized as the predominant Hb receptor, and is comprised of two NEAr transporter (NEAT) domains that act in concert to bind, extract, and transfer heme from Hb to downstream Isd proteins. Struc...
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Iron is an essential requirement for life for nearly all organisms. The human pathogen Staphylococcus aureus is able to acquire iron from the heme cofactor of hemoglobin (Hb) released from lysed erythrocytes. IsdB, the predominant Hb receptor of S. aureus, is a cell wall-anchored protein that is composed of two NEAT domains. The N-terminal NEAT domain (IsdB-N1) binds Hb, and the C-terminal NEAT...
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We have previously shown that IsdB, a conserved protein expressed by Staphylococcus aureus, induces a robust antibody response which correlates with protection in a murine challenge model. Here we investigate the role of cellular immunity in IsdB mediated protection using lymphocyte deficient SCID mice. As opposed to WT CB-17 mice the CB-17 SCID mice were not protected against a lethal challeng...
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ورودعنوان ژورنال:
- Mechanisms of Development
دوره 122 شماره
صفحات -
تاریخ انتشار 2005